Okay, so I was just reading Wikipedia about the CYP2D6 allele (yeah, I'm bored ), and I saw something quite interesting: apparently Diphenhydramine (DPH) acts as an inhibitor of CYP2D6 activity. And we all know that CYP2D6 plays a large part in metabolizing DXM. So...is DPH a potentiator of DXM (sure looks like it)!? Mabye this is common knowledge, but I hadn't heard about it. If I take like 75mg of DPH, will I trip harder / longer off DXM? Like as if I had the CYP2D6 defficiency? Anybody ever tried it? Sounds pretty cool.
Ps. I'm curious about lower doses of DPH with DXM, as I wouldn't really want to reach a DPH trip, just potentiate the DXM.